Recently, the National Institute on Aging, one of 27 Centers and Institutes of the NIH, held a consensus conference that addressed the complex topic of aging and transplantation. Those who spoke at and attended this conference identified the fact that older individuals experience specific problems after undergoing an organ transplant. Read More
To effectively address problems faced by organ transplant recipients, research efforts must be accelerated in the areas of tissue engineering (a promising means of developing new organs) and basic immunology (in order to reduce—and, ideally, eliminate—the need for immunosuppressive medications). Additionally, clinical research and policy initiatives must evolve so that all patients in end-stage organ failure, as well as their loved ones, may enjoy longer, healthier, and happier lives.
Below, you will find information on several research projects currently underway at the Northwestern Medicine Comprehensive Transplant Center.
In collaboration with a researcher at the University of Louisville, Dr. Leventhal is exploring a means by which a transplant recipient’s immune system could be made to look and act like the immune system of a non-related (i.e., no DNA similarities) donor.Read More
We are actively pursuing an endeavor that addresses the importance of preventing heart disease in individuals who have undergone kidney and pancreas transplants. Read More
With the goal of determining how, and to what degree, transplantation affects individuals’ QOL, the researchers are engaging in the formal, systematic assessment of transplant patients’ medical, emotional, and psychological health and wellness.Read More
Guided by the insights gained through his current work, Dr. Leventhal now seeks to launch a project that will focus on inducing immune tolerance without having to administer medications or therapies that weaken an organ recipient’s immune system in advance.Read More
Currently, Dr. Luo is embarking on a project that involves gathering spleen cells from a pancreas donor whose islet cells are being extracted for transplant.Read More
Northwestern’s, state-of-the-art facilities enable the thorough and progressive study of transplant immunology—a term that refers to the complex phenomena that characterize the immune system’s response to a transplanted organ. Read More
Given the spirit of collaboration and the many multidisciplinary pursuits that characterize the CTC, Jason Wertheim, MD, PhD, a Northwestern transplant surgeon with a background in bioengineering and immunology, has found the ideal environment in which to conduct his investigations in the area of bioengineering tissues and organs.Read More